About Sepax
Liquid Chromatography Services Capability
With more than 100 chromatographic resins and over 1000 different LC columns manufactured in house, Sepax has accumulated a broad scope of expertise to serve our customers for their various liquid chromatography needs for a wide range of small molecule and biopharmaceutical samples, including ADC, Antibody, Biosimilar, Carbohydrate, Cell Lysate, DNA/RNA, Fusion Protein, Glycoprotein, Heparin, Insulin, Membrane Protein, Natural product extract, Organic Acid, PEG/PEGylated Protein, Peptide, Polymer, Protein, Vaccine/VLP. Sepax’s liquid chromatography services include:
Analytical Chromatography
- Column and sample screening method development and optimization
- Validation services and on-site method transfer
- Stability and batch-releasing tests according to customers’ specifications
- In process sample quantitative method development
- USP monography testing
- LC/MS analyses
Prep and Process Purification
- Laboratory to process scales
- Mg to kg quantity sample preparation per customer specified purity
- Antibody and recombinant protein purification
- Native protein from natural sources purification
- Natural product purification
- Method development and scouting services
Custom Resin
- Resin surface chemistry modification (silica, polymer and agarose).
- Custom affinity resin conjugation.
- Pre-activated resin for ligand immobilization.
- Resin base bead development, including control of particle size, pore size, degree of cross-linkage, chemistry spacer arm, linker, etc.
- Custom resin manufacturing per customers’ specifications for lab-scale to production quantities using fully controlled reactors of 2000L volumes.