Surface Technologies
Sepax has developed a broad scope of unique chemical processes for synthesizing monomeric and polymeric thin films on both flat and particle surfaces. Our unique processes allow us to make neutral, cationic or anionic coatings with a controlled thickness from a few nanometers to more than 100 nm on internal or open surface uniformly. The primary Sepax surface chemistry expertise includes:
- Silane chemistry on SiO2 surface for reversed phase chromatography, such as C18, C8, C4, phenyl, etc.
- Silane chemistry on SiO2 surface for normal phase chromatography, such as cyano, amino, diol, etc.
- Chemical functional groups for ion exchange chromatography on PMA, PS/DVB and SiO2 surfaces
- Chemical functional groups for hydrophobic interaction chromatography on PMA and PS/DVB surfaces, such as butyl, ether, phenyl, etc.
- Affinity chemistries on agarose, polymer and SiO2 surfaces
- Nanometer thick hydrophilic coating for size exclusion chromatography
- Mixed-mode chemistry for ion-exchange and hydrophobicity on PMA and SiO2 surfaces
Sepax can also synthesize uniform coatings of polyacrylamide or polyethylene glycol on the internal surface of capillary tubes with ID from 15 to 75 µm. Those coated capillary columns with controlled or reversed EOF provide reliable and highly efficient separation (N >1.5×106/m for 20µm ID column) for Capillary Electrophoresis (CE), which has unique applications in high-throughput analysis, such as proteomics.